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学术动态
学术动态
“俄罗斯方块”有助于改善成人弱视
作者:    人气:4075    时间:2013-6-5 9:24:10

 

  中山大学眼科中心、 新西兰奥克兰大学、香港理工大学、加拿大麦吉尔大学等多家单位的联合研究人员使用流行的益智游戏“俄罗斯方块”治疗成人弱视,这项研究提供了直接证据:迫使双眼合作,可减轻对于弱视眼的抑制,增强大脑的可塑性,并且让大脑重新学习。研究结果发表在“Current Biology”杂志。

  弱视是儿童视力障碍最常见的原因,影响了约3%的人群。大脑处理信息不佳,导致优势眼抑制弱视眼。以往的治疗主要靠遮盖优势眼,强迫弱视眼进行工作,但这种方法仅在儿童中有效,成人往往效果不佳。

  “改善成人视力的关键在于为双眼提供合作的条件。”麦吉尔大学眼科研究所主任Robert Hess说。“成人的大脑具有相当程度的可塑性,这使得童年时视觉发育中断造成的后果有了治疗的可能。迫使眼睛共同努力,我们相信,将会改善弱视。”

  研究人员使用视频游戏俄罗斯方块锻炼受试者,纳入18名弱视成人患者。9名患者使用弱视眼进行游戏,优势眼被遮盖;另外9名患者则双眼共同参与,但一只眼只能看到方块落下,另一只眼只能看到静止的背景平面。

  两周后,后者弱视眼的视力和立体视觉明显改善。单眼组改为双眼训练后,视力也得到显著提高。

  北美的一项临床试验将在今年晚些时候对这种疗法进行评估,以评价其对于儿童的适用性。

  编译自:McGill University Health Centre (2013, April 22). Lazy eye disorder treated with video game Tetris. ScienceDaily. Retrieved April 23, 2013,

  Dichoptic training enables the adult amblyopic brain to learn

  Summary

  Adults with amblyopia, a common visual cortex disorder caused primarily by binocular disruption during an early critical period, do not respond to conventional therapy involving occlusion of one eye . But it is now clear that the adult human visual cortex has a significant degree of plasticity , suggesting that something must be actively preventing the adult brain from learning to see through the amblyopic eye. One possibility is an inhibitory signal from the contralateral eye that suppresses cortical inputs from the amblyopic eye . Such a gating mechanism could explain the apparent lack of plasticity within the adult amblyopic visual cortex. Here we provide direct evidence that alleviating suppression of the amblyopic eye through dichoptic stimulus presentation induces greater levels of plasticity than forced use of the amblyopic eye alone. This indicates that suppression is a key gating mechanism that prevents the amblyopic brain from learning to see.

 

(信息来源:医脉通)

 

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